Comparison of prothrombin complex concentrate and vitamin K1 in oral anticoagulant reversal.
نویسندگان
چکیده
منابع مشابه
Non-vitamin K Oral Anticoagulant Reversal
EVIDENCE DEFINITIONS Class I: Prospective randomized controlled trial. Class II: Prospective clinical study or retrospective analysis of reliable data. Includes observational, cohort, prevalence, or case control studies. Class III: Retrospective study. Includes database or registry reviews, large series of case reports, expert opinion. Technology assessment: A technology study which doe...
متن کاملNon-vitamin K Oral Anticoagulant Reversal
EVIDENCE DEFINITIONS Class I: Prospective randomized controlled trial. Class II: Prospective clinical study or retrospective analysis of reliable data. Includes observational, cohort, prevalence, or case control studies. Class III: Retrospective study. Includes database or registry reviews, large series of case reports, expert opinion. Technology assessment: A technology study which doe...
متن کاملUse of Prothrombin Complex Concentrate for Vitamin K Antagonist Reversal before Surgical Treatment of Intracranial Hemorrhage
BACKGROUND Oral anticoagulant therapy (OAT) is used to prevent/treat thromboembolism. Major bleeding is common in patients on OAT; eg, warfarin increases intracranial hemorrhage (ICH) risk. CASE A 71-year-old male on warfarin (to reduce stroke risk) presented at Accident and Emergency Minor Injuries Unit with headache after reportedly sounding 'drunk'. On triage, the patient appeared lucid an...
متن کاملReversal of Vitamin K Antagonist Therapy by Prothrombin Complex Concentrate before Thrombolysis for Acute Stroke
Vitamin K antagonist (VKA) frequently fails to prevent cerebral infarction, with 30% of VKA-treated patients experiencing ischemic stroke despite an international normalized ratio (INR) of ≥ 2 [1] . Intravenous (IV) thrombolysis is only recommended for patients with an INR of <1.7 [2] . Indeed, experimental results confirmed the high risk of post-thrombolytic hemorrhages at therapeutic INR leve...
متن کاملProthrombin complex concentrate-related thrombotic risk following anticoagulation reversal.
Dear Sirs, We read with interest the report of the meta-analysis performed by Dentali et al. on the adverse events after prothrombin complex concentrate (PCC) use for the emergency reversal of vitamin K antagonists (1). The authors identified a low incidence of thrombotic events and a non-significant difference between fourand three-factor PCCs at 1.8% and 0.7%, respectively. We do not wish to ...
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ژورنال
عنوان ژورنال: BMJ
سال: 1976
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.6027.83